Determinación del virus del papiloma humano en muestras de cáncer de las regiones anogenital y orofaringea procedentes del hospital SOLCA Núcleo de Loja

Abstract

Sexually transmitted infections continue to increase worldwide, representing a serious problem, in health, economic,and socialterms. Infection with human papillomavirus (HPV) is the most common sexually transmitted diseasein the world. HPV infection is associated with hyperplastic epithelial lesions, papillary carcinoma,and warty skin and different types of mucous membranes, including the anogenital tract, urethra, tracheobronchial,and nasalmucous membranes, larynx and oral cavity. The disease is producedby direct contact with infected skin or mucous membranes. In the presentstudy,40 paraffin tissue samples from anogenital and oropharyngeal region were analyzed by real-time PCR. Samples were collected fromtumor bank hospitalSOLCA core of Loja, between2010to 2013.Results demonstrated that 38.9%of valid samples had HPV, the most prevalent genotypes HPV 16 and HPV 58 with 29% and 17% respectively.