Aislamiento e identificación de metabolitos secundarios de la especie: Hypericum lancioides Cuatrec.

Abstract

The main objective of this study is the isolation and identification of secondary metabolites of Hypericum lancioides Cuatrec species. The isolation of these compounds was performed from ethyl acetate extract, which occurs in thin layer chromatography (CCF) better separation of compounds, various solvents were used in proportions with ascending polarity, the resulting fractions were purified by using micro columns and preparative chromatography. The elucidation of the structure of the isolated compounds was performed by NMR spectroscopic techniques (1 H-NMR, 13C-NMR), Identifying a flavonoid glycosylated known as quercetin 3-O-β-D-galactopyranoside with molecular formula C21H20O12, and a possible cinnamic acid compound whose identity has not yet been fully established. The antioxidant activity of the compound isolated is determined quercetin 3-O-β-D-galactopyranoside, using the DPPH method. From this result, it may suggest that this compound may be a potential antioxidant.