Evaluación de la actividad Citotóxica de extractos fúngicos de Zamora Chinchipe y Saraguro en diferentes líneas de Cáncer

Abstract

Cancer causes around a quintet of deaths worldwide; in the world every year die between 100 and 350 out of every 100.000 people; due to this disease (Lodish et al., 2009), therefore there are performed analysis of new therapies for its treatment, a significant source of metabolites for non-invasive treatments is the obtaining of samples as from fungal species. Assays performed have shown that the secondary metabolites present in species of Basidiomycetes present antitumoral suppressing effects, Cytotoxicity studies were conducted in the tumor lines of breast cancer (MCF-7 and ZR), Colon cancer (RKO) and Cerebral Astrocytoma (D-384), by employing excerpts from fungal species collected in the canton of Saraguro (Ingapirca Zone) and in the province of Zamora Chinchipe (Picuta and Campana Zones). The excerpts of the species with greater levels of cytotoxic activity studied were: Pycnoporus sanguineus (1), Trametes (4) and Collybia (2).