Please use this identifier to cite or link to this item: http://dspace.utpl.edu.ec/handle/123456789/19016
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dc.contributor.authorGuaman Ortiz, L.es_ES
dc.date.accessioned2017-06-16T22:02:47Z-
dc.date.available2015-06-11es_ES
dc.date.available2017-06-16T22:02:47Z-
dc.date.issued2015-01-01es_ES
dc.identifier10.1093/abbs/gmv077es_ES
dc.identifier.isbn16729145es_ES
dc.identifier.other10.1093/abbs/gmv077es_ES
dc.identifier.urihttp://dspace.utpl.edu.ec/handle/123456789/19016-
dc.description.abstractThe plant alkaloid berberine has been recently described as a promising anticancer drug. In order to improve its efficacy, several derivatives have been designed and synthesized, and found to be even more potent than the lead compound. Among the series of berberine derivatives we have produced, we identified five compounds able to heavily affect the proliferation of two human colon carcinoma cell lines, i.e. HCT116 and SW613-B3. Remarkably, the active compounds are characterized by high fluorescence emission property and ability to induce autophagy.es_ES
dc.languageIngléses_ES
dc.subjectapoptosises_ES
dc.subjectautophagyes_ES
dc.subjectberberinees_ES
dc.subjectcolon canceres_ES
dc.subjectfluorescencees_ES
dc.titleEffect of new Berberine derivatives on colon cancer cellses_ES
dc.typeArticlees_ES
dc.publisherActa Biochimica et Biophysica Sinicaes_ES
Appears in Collections:Artículos de revistas Científicas



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