Please use this identifier to cite or link to this item: http://dspace.utpl.edu.ec/jspui/handle/123456789/19172
Title: Development of anticancer drugs based on the hallmarks of tumor cells
Authors: Bailon Moscoso, N.
Romero Benavides, J.
Keywords: Cancer
Cancer cell hallmarks
Drug design
metadata.dc.date.available: 2017-06-16T22:03:04Z
Issue Date: 1-Jan-2014
Publisher: Tumor Biology
Abstract: Cancer remains a public health problem with a high unmet medical demand. However, in recent decades, the knowledge of several functional molecular and biological traits that distinguish tumor cells from normal cells, known as the hallmarks of cancer as described by Hannahan and Weinberg, has led to new and modern therapeutic approaches against this disease. Most cancer drugs are deliberately developed for specific molecular targets that involve these hallmarks. In this review, we address the currently available cancer drugs and development of new drugs from the perspective of their interaction with these hallmarks as well as the pathways and mechanisms involved. © 2014 International Society of Oncology and BioMarkers (ISOBM).
metadata.dc.identifier.other: 10.1007/s13277-014-1649-y
URI: http://dspace.utpl.edu.ec/handle/123456789/19172
ISBN: 10104283
Other Identifiers: 10.1007/s13277-014-1649-y
Other Identifiers: 10.1007/s13277-014-1649-y
metadata.dc.language: Inglés
metadata.dc.type: Article
Appears in Collections:Artículos de revistas Científicas



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