Encuesta serológica en la población ecuatoriana para detectar IgG anti-SARS-CoV-2 causante de COVID-19

Abstract

Abstract:At the beginning of the year 2020, health emergency protocols were activated worldwide; consequence of the state of pandemic declared by the WHO given the rapid spread of the SARS-CoV-2 virus that causes COVID-19. Currently, COVID-19 is responsible for 1.8% mortality and 33.2% morbidity in the Americas. Several scientists studied the behavior of this pathogen, confirming that two immune responses are involved in the infection: innate and adaptive. For this reason, our study determined the seroprevalence of the IgG anti-SARSCoV-2 antibody in patients from Loja, it was quantified by the in-house ELISA technique and compared with Immunochromatography. Of 328 samples collected, the seroprevalence was 33.2% (n=109) using the ELISA technique, with sensitivity and specificity of 93.6% and 100%, respectively, and the immunochromatographic technique obtained a lower seroprevalence of 28.4% (n=109). =93), with a sensitivity of 96.02% and a specificity of 99.07%. Finally, the most susceptible population was men aged 18 to 40 years with 65.22% (n=30), asymptomatic people represented 20.18% (n=22) and the most common main symptom was headache. with 71.43% (n=30)