Determinación de la actividad biológica del aceite esencial de Melaleuca ericifolia

Abstract

Abstract: In this study, the essential oil of Melaleuca ericifolia was evaluated; a species belonging to the Myrtaceae family known for having medicinal properties composed at least by 3000 species, native to Australia and Tasmania. The essential oil was purchased through the Aromavida company. Its chemical composition was determined by gas chromatography coupled to gas spectrometry (GC-MS) on the non-polar column (TR5-MS). The antimicrobial activity was tested with Gram positive and Gram negative, the antifungal activity was determined with yeasts or fungi. The properties antioxidants known as essential oil radical scavenging was determined through the DPPH and ABTS spectrophotometric assays. The anticholinesterase activity is measured by the spectrophotometric method that determines the inhibitory concentration of acetylcholinesterase. The chemical composition yielded a total of 48 identified compounds. which are equivalent to 95.85% of its composition. The major compounds (greater than 1% of relative abundance) were 1,8-cineole (61.85%), limonene (11.23%), &#945;-terpineol (7.99%), &#945; pinene (4.97%), &#946;-pinene (3.71%), cymene <&#961;-> (1.11 %) and terpinen-4-ol (1.03%). The AE does not I present antimicrobial, antifungal and antioxidant activity. Within the activity acetylcholinesterase inhibitor presented moderate activity with an IC50 value 73.61 µg/mL.