Evaluación del daño genotóxico mediante el ensayo cometa en población expuesta a material particulado 2.5 residentes en la zona céntrica de la ciudad de Cuenca – Ecuador.

Abstract

Environmental pollution is a problem for the health of the population, within the contaminants is the particulate material 2.5 (MP2.5) able to cross the respiratory system and pass into the bloodstream causing DNA damage. The objective was to evaluate the genotoxic damage in the inhabitants of the central zone of the city of Cuenca - Ecuador by exposure to MP2.5 through the comet test. The cases of the study were inhabitants of the zone where the monitoring of the MP2.5 was high and for the controls the monitoring of the MP2.5 was low. The analysis was performed on blood samples, processed in the Human Genetics, Microbiology and Clinical Biochemistry section of the Universidad Técnica Particular de Loja, where damage to the DNA of the cells was evaluated. According to the parameters of the trial, the two populations studied did not present statistically significant differences in the data; general aspects were related such as sociodemographic characteristics, aspects of fertility and reproduction, exposure agents, medication consumption and incidence of pathologies.