Aspectos demográficos y estilo de vida que influyen sobre daño genético y estado de salud de población expuesta a pesticidas en el cantón Calvas

Abstract

Abstract:Substances such as pesticides are toxic compounds with potential to cause damage to the structure or functions of an exposed organism. Pesticides can cause harmful biological effects in animals and their offspring in the medium and long term. Exposure to pesticides has also been linked to DNA damage, and in this case abortions, degenerative diseases and cancer can occur. The objective of this work was to establish a compromised state of health, and evidence of genetic damage in women exposed indirectly to pesticides in Chimchanga and Colaisaca in southern Ecuador. Women were subjected to hematological, biochemical, micronucleous analysis and nuclear abnormalities in oral cells. Hepatic toxicity was observed in Colaisaca women (Aspartate Aminotransferase and alanine aminotransferase) and an increase in the micronucleous rate in Colaisaca and Chimchanga individuals, in addition to observing more DNA damage through markers such as NBuds and Notch in Colaisaca, being contrary to the answer in Chimchanga, where the indicators of cell death are found through Karyolisis, Karyorrhexis.