Aislamiento, identificación y actividad antioxidante de metabolitos secundarios a partir de la especie Piper pseudochurumayu.

Abstract

Abstract:In the present investigation was carried out the phytochemical study of the medicinal plant Piper pseudochurumayu commonly known as "matico", the plant was collected in the sector Numbani of the province of Zamora Chinchipe. From the leaves were obtained 3 extracts: ethyl acetate, methanol and methanol-water (7:3). For the characterization of the isolated compounds, spectroscopic techniques of NMR, GC-MS, were used and corroborated with the data from literature. A compound belonging to the family of terpenes, specifically a diterpene known as kaurenoic acid, was isolated, and a mixture of three sesquiterpenes (α-Muurolol, epi-α-Muurolol y α-Selin-11-en-4-ol), was identified by GC-MS. The antioxidant activity of the extracts analyzed by the DPPH method was poor according to the antioxidant activity index: the ethyl acetate extract showed a value of (0.02) and a methanolic extract (0.26)