Aislamiento, caracterización de metabolitos secundarios y evaluación biológica de la especie Onoseris salicifolia

Abstract

Abstract:n the present phytochemical study of secondary metabolites of the species Onoseris salicifolia, 4 compounds were identified: a mixture of two terpenes named Lupeol and Germanicol, two glycosylated phenols known as Arbutin, and (2S, 3S, 4S, 6R) - 4- (hydroxymethyl) -6- (3- hydroxyphenoxy) tetrahydro-2H-pyran-2,3,5-trio. Spectroscopic techniques such as CC, CCF and NMR were used for elucidation of the compounds and then corroborated with bibliographic data, the antimicrobial activity of the total extracts was evaluated for four microorganisms of bacterial species and one of fungus species, using the method of broth microdilution. Total extracts had no activity against the microorganisms used and only the methanol extract had activity in the α-glucosidase method (229.1 μg / ml)