Utilidad de la procalcitonina como marcador diagnostico temprano en choque septico neonatal frente a concentraciones de PCR y recuento leucocitario

Abstract

Abstract:In Ecuador, neonatal bacterial sepsis represents the third cause of infant mortality. In this work, it was proposed to quantify procalcitonin, CRP and leukocyte count and relate the values ​​obtained in order to determine the usefulness of procalcitonin as an early diagnostic marker in neonatal septic shock, with a universe consisting of 98 hospitalized neonates in the area of ​​neonatology from Isidro Ayora Hospital in the city of Loja, of which 60 newborns met the inclusion criteria. The electrochemiluminescence technique was used to determine procalcitonin, immunoturbidimetry for PCR and fluorescent flow cytometry for leukocyte count. It is important to recommend to treating doctors that when the CRP values ​​and leukocyte count are altered or not, a more effective, sensitive and specific test such as Procalcitonin is performed so that the specific treatment for infection can begin that the test is altered.