Percepción de quorum en bacterias pertenecientes al género Staphylococcus

Abstract

Abstract: At a global level, bacterial resistance has become a problem, especially in the Staphylococcus genus. This thesis studies the correlation between antibiotic multi-resistance and quorum sensing (PQ). PQ is a communication mechanism that occurs through population density which allows them to coordinate behaviors. In the development of the methodology, a bibliographic review was carried out using databases such as PubMed, Scopus, Web of Science and others. 403 articles published between 2019 and 2014 were obtained, applying the inclusion and exclusion criteria, 40 were selected. In conclusion, there is a relationship between PQ and antibiotic multi-resistance in Staphylococcus, this is known from studies that show that there are PQ regulatory genes. In South America, high percentages of resistance were found (21.4%-54%) compared to Europe (14.8%-22.5%), identifying genes essential for the formation of biofilms and resistance such as icaA, icaD and ebpS. However, the Agr system regulates virulence and resistance, facilitating the mechanisms of biofilms and gene expression. The variations that occur in different regions suggest that the health system influences bacterial resistance.