Identificación, composición química y actividad biológica de una especie hepática del sur del Ecuador

Abstract

Abstract: In this research, a phytochemical study of the plant species Syzygiella rubricaulis and its biological activity was carried out. The plant material was collected in the sector el tiro, the study of the chemical composition of the plant species was carried out by analytical techniques such as TLC and column chromatography, in which silica was used to assemble the phase and a kind of homogeneous mixture was made with the extract, silica and methanol, The collected tubes were subjected to TLC analysis for the determination of pure compounds. During this procedure, 3 apparently pure fractions were obtained, although the weight obtained from these fractions was not sufficient for a precise identification. For the determination of the biological activity, static tests were carried out with the methanolic extract of the species, the compounds obtained were evaluated with RNM to determine the compounds, however, they were not completely pure, which made the final identification difficult, the plant species showed a great antioxidant potential and also presents inhibitory activity against acetylcholinesterase, although it is less potent than Donepezil, a known and clinically used inhibitor.