Efectividad de una intervención en salud sobre el perfil lipídico en pacientes con Riesgo de Diabetes Mellitus Tipo 2

Abstract

Abstract: Type 2 Diabetes Mellitus (T2DM) is a chronic, non-communicable disease that causes death. In Ecuador, it has been diagnosed in 6.6% of the population (45-69 years old). However, the effectiveness of interventions based on the Diabetes Prevention Program has not been studied in the city of Loja. Objective: To evaluate the effectiveness of the intervention Transform your life with daily changes on lipid profile control in patients at risk of Type 2 Diabetes Mellitus (T2DM). Materials and methods: Non-randomized, quasi-experimental, before-and-after study in individuals with ≥12 points according to FINDRISC (moderate to very high risk). The intervention group (n=128) received 10 sessions of a three-pronged strategy (nutrition, physical activity, and motivation) adapted to the local context over 4 months, plus usual care, while the control group participants (n=28) received only usual care. Lipid profile (total cholesterol, triglycerides, HDL, and LDL), as well as clinical and anthropometric parameters, were assessed at baseline and at the end of the intervention. Results: Women had higher RDM2 based on anthropometric variables. HDL had the strongest association and was inversely proportional to RDM2. No statistically significant difference was observed in any lipid profile variable between the pre- and post-intervention stages. Conclusion: The intervention did not have a significant effect on the lipid profile in the intervention group.