Órganos bioimpresos en 3D a partir de células madre autólogas: estado del arte químico-biológico y perspectivas clínicas: una revisión bibliográfica.

Abstract

Abstract: 3D bioprinting of organs and tissues using the body's own stem cells is a groundbreaking concept in regenerative medicine. This is because it can create structures that are compatible with the body and function properly. This review of studies sought to analyze the advances, challenges, and trends regarding bioprinting materials, printing techniques, cell survival, and the level of technological advancement. The research followed the PRISMA method, in conjunction with the Publish and Perish software, and considered approximately 400 scientific studies published between 2016 and 2026. VOSviewer was used for bibliometric analysis of the data. The results showed that natural and hybrid materials are preferred for bioprinting. Mesenchymal stem cells and extrusion printing techniques were also widely used. Furthermore, it was observed that there is increasing research in this area. However, there are still technical and regulatory issues hindering its widespread clinical use. 3D bioprinting of organs and tissues is a growing field. More studies are needed to overcome the challenges and realize its benefits.