Evaluación comparativa del test de Morisky-Green de 4 ítems y el MMAS-8 en la medición de adherencia terapéutica: un análisis bibliográfico

Abstract

Abstract: Therapeutic adherence is a critical determinant of the management of chronic diseases; therefore, its accurate measurement is essential in pharmaceutical practice. The objective of this study was to compare the methodological quality and measurement capacity of the four-item Morisky-Green test (MMAS-4) and the eight-item Morisky Medication Adherence Scale (MMAS-8) through an analytical review of five studies selected according to explicit eligibility criteria and evaluated using an adaptation of the CASP tool. The studies met high methodological quality standards (average 8.4/10). The findings show that the MMAS-8 has greater discriminative power and sensitivity than the MMAS-4, although its internal consistency was heterogeneous (Cronbach s alpha between 0.40 and 0.70) and its specificity was low. It is concluded that the MMAS-8 is preferable for individualized pharmacotherapy monitoring, while the MMAS-4 remains useful as a screening tool. Local validation in the Ecuadorian population is recommended prior to systematic implementation.