Estudio de la aplicación de modelos markovianos en el alineamiento de secuencias y árboles filogenéticos para ADN y proteinas

Abstract

This paper aims to provide both theoretical and practical foundations that will help us to have clear ideas in the field of Bioinformatics, but mainly about the study of Markovian Models. Nowadays technological advances have made it possible to access information in a truthful and timely manner, especially in Bioinformatics, streamlining processes thanks to the tools that have been built such as large databases, computer tools, etc. As a result of this thesis, it has been divided into three well-defined phases and correctly structured by its broad development. In Phase 1: Research and compilation of the most important and demanding information such as sequence alignment, phylogenetic trees and Markov models and mainly how DNA and proteins are formed. Phase II: All the previously investigated has been applied in order to reach the construction of the phylogenetic trees by means of markov models using sequences of either DNA or Proteins. In the PHASE (U: We present the results of the investigation compared with some bioinformatic tool that also constructs phylogenetic trees through Markovian Models.