Valores referenciales de creatinina en la ciudad de Loja en pacientes del Hospital Militar

Abstract

Abstract: The determination of serum creatinine is the main parameter to assess kidney function. Creatinine reference values ​​are used to differentiate kidney pathologies, for prognosis and evaluation of risk factors, as well as to monitor the effectiveness of a treatment. The purpose of this study is to establish creatinine reference intervals in the city of Loja. Serum samples were taken from 300 male patients and 300 female patients, prior to the application of a test to investigate the inclusion and exclusion criteria in which chronic and acute pathologies were basically ruled out, as well as the intake of substances or medications that interfere with the result. It was carried out between October 2009 and September 2010, in the Clinical Laboratory of the Military Hospital of Loja. Venous blood was extracted from the studied universe, which was manipulated with the creatinine reagent and subjected to the spectrophotometer applying the colorimetric method for its respective result. The reference intervals obtained were: Creatinine: 0.6 to 1.2 mg/dL in females and 0.7 to 1.3 mg/dL in males. An interindividual difference is observed between both sexes, with a lower creatinine level in women due to their muscle mass. It is important to emphasize that in our study we obtained slightly higher reference ranges compared to those of other ethnicities.