Aislamiento e identificación de metabolitos secundarios a partir de Triplaris cumingiana con posible actividad antiparasitaria

Abstract

In the present investigation we report the phytochemical study the aerial parts of Triplaris cumingiana by open column chromatography; obtaining three vegetal extracts in hexane (Hex), ethyl acetate (AcOEt) and methanol (MeOH). Of the AcOEt extract we obtained a whitish compound known as 2-hydroxy, 4-6 dimethoxyacetophenone (1) weighing 46,4 mg and with a Rf of 0,6 which was eluted in Hex:AcOEt 7:3 and whose melting point is 67-68 °C; also a crystallized sample was obtained, which has not been identified, eluted in EtOAc:MeOH 4:6, weighing 30,3 mg and whose melting point is above 300 °C, it suspected that is an inorganic salt, which was analyzed by X ray diffraction and It has not been identified because it not exist in the corresponding database; and of the methanol extract was obtained a yellow orange color substance, eluted in CH2Cl2:MeOH 90:10 weighing 40,8 mg and with a melting point of 295-300 °C, soluble in pyridine that is in process of identification, also the compound 1 isolated in AcOEt extract was obtained; the isolated compounds were identified by spectroscopic methods as gas chromatography coupled with mass spectroscopy GC/MS and proton nuclear magnetic resonance 1H NMR and 13C NMR carbon.