Análisis topológico de De Bruijn Graphs generados a partir de datos metagenómicos

Abstract

The study of metagenomics, with the use of new generation sequencing technologies(NGS), has allowed to the human being to be able to sequence a large number of genomes in a very short time. The amount of information is so great that more and more frequently the term Big Data is used to refer to the information, which is ready in the databases to be analyzed. However, there are several problems to analyze this data at an appropriate pace, which have become in computational challenges nowadays. The problems might be sorted in two specific kinds, the lack of programs for analysis,and perhaps most importantly the lack of training of staff in the analysis and interpretation of genomic data. Then, the use of the De Bruijn Graphs for Genomic Assembly will allow us to analyze the topological properties of the graphs, depending on the phylogenetic relationships of microbial species found in metagenomic samples of soil.