Aislamiento y caracterización de metabolitos secundarios de la especie Macrocarpaea lenae

Abstract

In southern Ecuador, in the community of Saraguro a species called Macrocarpaea Lenae, commonly known as Cerro snuff, for their different benefits, a phytochemical study for the isolation and characterization of secondary metabolites was performed was collected. This process began with the collection of the species in the canton of Saraguro. three extracts were obtained, in order to choose the ethyl acetate extract showing greater amount of compounds contain, based on the richness of compounds given by thin layer chromatography. It was continued fractionation by column chromatography, and the resulting fractions were purified by microcolumns. During the study, four iridoid compounds isolated nature; two had not been isolated previously considering them as new compounds, derived from the other two compounds known as: Swerosido and Djalonenol. GC-MS, IR, NMR and computer calculations that will confirm the stereochemistry of the new compounds: for structural identification techniques as employed.