Complicaciones asociadas a la enfermedad de Kawasaki en niños

Abstract

Abstract:Kawasaki disease (KD) or Lymphonodular Mucocutaneous Syndrome is a systemic vasculitis that affects medium/small arteries, in 85% of cases affects children <5 years, being more involved men. The objectives are to determine the complications associated with EK in the pediatric population, and the risk factors associated with them. The methodology used for this literature review was the search in electronic databases: Pubmed, Lilacs, Scielo and Scopus of studies on patients with complications of KD. Of the 17 articles selected, it was possible to show that there are various complications, among which a greater association was observed in very young children, reporting cardiovascular complications (mainly coronary); neurological (aseptic meningitis, neurosensory hypoacusia); ophthalmological; and isolated cases of macrophage activation syndrome, Grisel syndrome and peripheral gangrene. Complications are also reported after the administration of KD treatment. As conclusions were obtained that the most frequent complications are cardiovascular, followed by neurological, ophthalmological, among others. Risk factors were early age; male sex; incomplete KD; leukocytosis; hypoalbuminemia; elevated ESR-CRP; and late treatment with intravenous immunoglobulin.