Estudio de estabilidad acelerada de una solución tópica a base del extracto de Piper ecuadorense

Abstract

Abstract: In the present research, a study of accelerated stability of a topical solution whose active ingredient is pinocembrin, obtained from a vegetal specie called Piper ecuadorense was development. For this, we began with the manufacturing process of a formula established in a previous study, to wich we made quality controls including: organoleptic (color, smell and appearance) and physical-chemical proprieties (pH, density and viscosity); and the concentration of pinocembrin was determinated with an UV-visible spectrophotometer. In addition, a microbiological study was perfomed, including total coliforms - E. Coli, S aureus, mesophilic aerobes and yeasts. These tests were all negative demonstrating the absence of microorganisms. Therefore, this lotion was microbiologically stable during the test time. Finally, with the data obtained in the present study, the lotion shows a shelf life of three months.