Determinación de la actividad biológica del aceite esencial de Minthostachys verticillata

Abstract

Abstract: Minthostachys verticillata,aromatic semi shrub native to South American countries, used in traditional medicine; its oil was extracted by hydro-distillation and analyzed by gas chromatography, identifying the presence of 100 compounds, destacando piperitone (25.65%), carvacrol acetate (14.53%), menthone (8.42%) and carvacrol (6.57%). Tests were carried out to evaluate the biological activity of the essential oil, where the antibacterial activity was moderate against Campylobacter jejuni and null against other bacterial strains under study. In terms of antifungal activity, moderate activity was observed against Aspergillus niger and null against Candida albicans, in terms of antioxidant activity a concentration of 99.46 µg/mL ± 0.20 was obtained in the ABTS method and in the DPPH method a concentration of 5685.21 ± 5.18 µg/mL was obtained, showing a moderate capacity by the ABTS method. However, the acetylcholinesterase inhibition of the oil presented an IC50 of 23.67 µg/mL ± 1.01 highlighting the relevance of this activity. These results suggest the potential of Minthostachys verticillata in health-related applications, especially in terms of antioxidant and anticholinesterase activity.