Estudio fitoquímico de los extractos apolares de la especie ecuatoriana Croton rivinifolius Kunth

Abstract

In the present phytochemical study it was possible to obtain the total methanolic extract of the leaves of the Ecuadorian species Croton rivinifolius Kunth, from which fractions of partition of hexane, dichloromethane, ethyl acetate and methanol / water were formed. In which, from the fraction of hexane partition, a mixture in which Squalene (1) predominated as a major compound was isolated and identified by GC-MS. On the other hand, the ethyl acetate partition fraction was isolated by column chromatography and characterized by the NMR spectroscopic technique two compounds, one of flavonoid origin known as Tiliroside (2), and another of glycosylated iridoid origin called Swerosido (3), the same one that is reported for the first time in our case for the Croton genus. Finally, the methanolic extract of the stems was obtained from which it was possible to isolate and characterize a compound of alkaloid origin known as Isocorydine (4). All the compounds that were identified are of great importance, because they present a great variety of biological activity.