Evaluación genotóxica en la población expuesta a plaguicidas en el cantón Calvas

Abstract

The use of pesticides has become widespread worldwide in recent years and their consumption and variety have increased dramatically, in response to the growth of cities, encouraging the population to seek economic income as well as family support. The main problem is its indiscriminate use and the lack of basic safety standards; increased environmental pollution and damage to the health of the people who use them. Taking into account the lack of studies in our population, the genotoxic damage produced by pesticides in the inhabitants of Cantón Calvas was evaluated. The study was of the case and control type, the participants were men and women of productive age, evaluating hematological values, blood chemistry and genotoxic damage by means of the micronucleus test in cells of the buccal epithelium. Most of the parameters did not show changes; only liver enzymes (SGOT, TGP and GGT) were found elevated in the group of exposed women. In the genotoxic evaluation, significant differences were found in the presence of micronuclei, outbreaks and binucleated cells in exposed women and men.