Determinación de la composición química, propiedades físicas y evaluación de la actividad biológica del aceite esencial de la especie Piper barbatum (Cordoncillo) del cantón Macará, provincia de Loja

Abstract

Abstract:Piper barbatum known as Cordoncillo, is an aromatic, perennial plant that grows in humid and low soils, the essential oil of this species was extracted by distillation. The chemical composition was determined by gas chromatography coupled to CG / MS mass spectrometry and to the ionization detector called CG / FID. The biological activity was evaluated by the broth microdilution (CMI) method. We identified 41 with an identification percentage of 95.13% of the oil. The major compounds were: β-Bisabolene (15.99%), (E) -Caryophyllene (9.03%), α-Selinene (10.07%), β-Selinene (8.92%), α-Phellandrene (3.93%), α-Eudesmol (3.28), Selina-3.7 (11) -diene (3.44%), Germacrene-D (4.60%), Alloaromadendrene (2.92%) and α-Eudesmol (3.28). The density of the oil was 0.97 g / cm3, the refractive index of 1.46 and the optical activity of -14.58 °. The essential oil of P. barbatum showed moderate activity against Gram-positive strains, while it was inactive against Gram-negative strains.