Estudio fitoquímico y evaluación de la actividad genotóxica de extractos polares de Solanum betaceum (tomate de árbol)

Abstract

Abstract: Solanum betaceum Cav. It is an exotic fruit originating in South America; It has beneficial properties for health due to a nutritional composition. The objective of this project was to establish the phytochemical content and evaluate the genotoxic activity of the polar extracts of pulp, bark and seed of two species of Solanum betaceum Cav., For this two species are needed: Orange - Elliptical and Purple lyophilization, maceration and broken vapor. In addition, infrared thin layer chromatography, phytochemical screening was performed and finally the genotoxic activity of the extracts was evaluated. 14 extracts were obtained, it was evidenced that the chromatographic profile of all the extracts was different, several functional groups were identified by means of infrared, highlighting the presence of vitamin A in the ethanolic extract of the seed of the Morado species. The presence of some compounds. Finally, some extracts applied at a dose of 100 μg / ml for 24 hours to CHO-K1 cells cause genotoxic damage, with the ethanol: water extract of 1: 1 seed from both species causing the most damage to the cells.