Evaluación de la actividad inhibitoria frente a Campylobacter jejuni y Arcobacter butzleri, de extractos totales de hongos basidiomicetos y actinobacterias marinas, colectadas en el Sur del Ecuador.

Abstract

Abstract: Gastrointestinal infection is a disease with high incidence. The bacterial group represents 28% and the Campylobacteraceae family is the fourth cause worldwide, due to the fact that the transmission is by oral route with contaminated animals or food, as well as unfavorable health, economic, social, and environmental factors. The Basidiomycetes fungi and sea Actinobacteria have remarkable antimicrobial bioactivity, so in this research, 44 extracts were analyzed, including Basidiomycetes fungi collected in San Lucas parish and Saraguro canton, and sea Actinobacteria obtained from the UTPL strain. The antibacterial capacity was evaluated against fastidious organisms such as Campylobacter jejuni and Arcobacter butzleri, through the method of Microdilution in broth to determine the minimum inhibitory concentration (MIC), using the supplemented CAMBH medium and microaerophilic atmosphere (5%O2, 10%CO2) for 48H at 42° C for C. jejuni and A. butzleri at 30°C without microaerophilic. Within the outstanding results, there is the Daldinia sp. fungus with a MIC of 250 ug/mL and Trichaptum sp. with 59.94ug/mL and 61.05ug/ mL against Campylobacter jejuni.