Estudios biofarmacéuticos de una nanoemulsión de crisaborole

Abstract

Abstract: This project consists of conducting a biopharmaceutical evaluation of the release and permeation parameters of the drug crisaborole contained in a nanoemulsion and nanogels. This topical medication is used for the treatment of atopic dermatitis (eczema) and psoriasis, due to its effective anti-inflammatory properties. Biopharmaceutical studies of drug release from the nanoemulsion and its nanogels are essential to ensure that the drug reaches its target site and exerts its pharmacological action. Once optimal results have been achieved with the crisaborole nanoemulsion, its transformation into a nanogel formulated using polymers incorporated into the nanoemulsion will be explored to improve its viscosity, extensibility, and retention time of the formulation in the treated area.