Aislamiento y caracterización de metabolitos secundarios aislados de las especies Gynoxys cf. pulchella y Baccharis latifolia

Abstract

The Asteraceae family is widely distributed in the Andean region of Ecuador. Few of these species in this area have been chemically studied, for this reason the information about the secondary metabolites they contain is limited. In this research, the ethyl acetate extracts of the species Gynoxys cf. pulchella and Baccharis latifolia, belonging to the family Asteraceae were evaluated phytochemically. The betulin (1) triterpene was isolated from the species G. cf. pulchella; while the sesquiterpene (4S) -7-oxo-8-hydroxybisabola-1 (2), 12 (13) -diene (2) and 5-hydroxy flavone, 4 ', 7-dimethoxyflavone (3) were isolated from B . latifolia. The structures of all compounds were established by spectroscopic methods. Additionally, the in vitro antibacterial activity of the extracts in ethyl acetate species G. cf. B. pulchella and latifolia, were evaluated against seven bacterial strains using the broth microdilution method, none of the extracts showed activity at the concentrations tested. .